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Loss of Endothelial Hypoxia Inducible Factor‐Prolyl Hydroxylase 2 Induces Cardiac Hypertrophy and Fibrosis

BACKGROUND: Cardiac hypertrophy and fibrosis are common adaptive responses to injury and stress, eventually leading to heart failure. Hypoxia signaling is important to the (patho)physiological process of cardiac remodeling. However, the role of endothelial PHD2 (prolyl‐4 hydroxylase 2)/hypoxia induc...

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Detalles Bibliográficos
Autores principales: Dai, Zhiyu, Cheng, Jianding, Liu, Bin, Yi, Dan, Feng, Anlin, Wang, Ting, An, Lingling, Gao, Chen, Wang, Yibin, Zhu, Maggie M., Zhang, Xianming, Zhao, You‐Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751916/
https://www.ncbi.nlm.nih.gov/pubmed/34743552
http://dx.doi.org/10.1161/JAHA.121.022077