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Control of Tumors by Antigen-Specific CD8(+) T Cells through PDL1-Targeted Delivery of Antigenic Peptide

Tumor antigen-specific T cell function is limited by immune tolerance in the tumor microenvironment. In the tumor microenvironment, tumor cells upregulate PD-L1 expression to promote T cell exhaustion by PD-1/PD-L1 interactions and undergo mutations to avoid being targeted by tumor antigen-specific...

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Detalles Bibliográficos
Autores principales:	Feng, Po-Hao, Wang, Xiaoxu, Ferrall, Louise, Wu, T.-C., Hung, Chien-Fu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752305/ https://www.ncbi.nlm.nih.gov/pubmed/35028321 http://dx.doi.org/10.1155/2022/9054569

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