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Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?

Fahr's syndrome is a rare, genetically dominant, inherited, neurological disorder characterized by abnormal deposits of calcium in the basal ganglia and the cerebral cortex. Symptoms include motor dysfunction, dementia, headache, spastic paralysis, abnormal ocular findings and seizures. Hypopar...

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Autores principales: Palu, Gabriele, Moraes, Samia T, Romaniello, Gabriela, Zatorre, Luis O, Seixas, Luiza K, Miyazima, Rafael, Lenci Marques, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752340/
https://www.ncbi.nlm.nih.gov/pubmed/35036185
http://dx.doi.org/10.7759/cureus.20342
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author Palu, Gabriele
Moraes, Samia T
Romaniello, Gabriela
Zatorre, Luis O
Seixas, Luiza K
Miyazima, Rafael
Lenci Marques, Gustavo
author_facet Palu, Gabriele
Moraes, Samia T
Romaniello, Gabriela
Zatorre, Luis O
Seixas, Luiza K
Miyazima, Rafael
Lenci Marques, Gustavo
author_sort Palu, Gabriele
collection PubMed
description Fahr's syndrome is a rare, genetically dominant, inherited, neurological disorder characterized by abnormal deposits of calcium in the basal ganglia and the cerebral cortex. Symptoms include motor dysfunction, dementia, headache, spastic paralysis, abnormal ocular findings and seizures. Hypoparathyroidism is the most common endocrine disorder related to this syndrome, however, there are other metabolic, infectious and genetic causes. This is a case report of a Fahr’s syndrome patient presenting a three-month history of self-limited partial epileptic seizures. His cranial CT had bilateral symmetrical calcifications of the basal ganglia, subcortical tissue and dentate nucleus whereas his laboratory findings were compatible with hypoparathyroidism.
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spelling pubmed-87523402022-01-14 Could Fahr’s Syndrome Have More Than One Simultaneous Etiology? Palu, Gabriele Moraes, Samia T Romaniello, Gabriela Zatorre, Luis O Seixas, Luiza K Miyazima, Rafael Lenci Marques, Gustavo Cureus Endocrinology/Diabetes/Metabolism Fahr's syndrome is a rare, genetically dominant, inherited, neurological disorder characterized by abnormal deposits of calcium in the basal ganglia and the cerebral cortex. Symptoms include motor dysfunction, dementia, headache, spastic paralysis, abnormal ocular findings and seizures. Hypoparathyroidism is the most common endocrine disorder related to this syndrome, however, there are other metabolic, infectious and genetic causes. This is a case report of a Fahr’s syndrome patient presenting a three-month history of self-limited partial epileptic seizures. His cranial CT had bilateral symmetrical calcifications of the basal ganglia, subcortical tissue and dentate nucleus whereas his laboratory findings were compatible with hypoparathyroidism. Cureus 2021-12-11 /pmc/articles/PMC8752340/ /pubmed/35036185 http://dx.doi.org/10.7759/cureus.20342 Text en Copyright © 2021, Palu et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Palu, Gabriele
Moraes, Samia T
Romaniello, Gabriela
Zatorre, Luis O
Seixas, Luiza K
Miyazima, Rafael
Lenci Marques, Gustavo
Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title_full Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title_fullStr Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title_full_unstemmed Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title_short Could Fahr’s Syndrome Have More Than One Simultaneous Etiology?
title_sort could fahr’s syndrome have more than one simultaneous etiology?
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752340/
https://www.ncbi.nlm.nih.gov/pubmed/35036185
http://dx.doi.org/10.7759/cureus.20342
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