Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target

Tuberculosis (TB) is the leading cause of death from a single infectious agent and in 2019 an estimated 10 million people worldwide contracted the disease. Although treatments for TB exist, continual emergence of drug-resistant variants necessitates urgent development of novel antituberculars. An im...

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Detalles Bibliográficos
Autores principales: Adams, Oliver, Deme, Justin C., Parker, Joanne L., Fowler, Philip W., Lea, Susan M., Newstead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Short Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752444/
https://www.ncbi.nlm.nih.gov/pubmed/34242558
http://dx.doi.org/10.1016/j.str.2021.06.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752444/
https://www.ncbi.nlm.nih.gov/pubmed/34242558
http://dx.doi.org/10.1016/j.str.2021.06.013

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