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Cryo-EM structure and resistance landscape of M. tuberculosis MmpL3: An emergent therapeutic target
Tuberculosis (TB) is the leading cause of death from a single infectious agent and in 2019 an estimated 10 million people worldwide contracted the disease. Although treatments for TB exist, continual emergence of drug-resistant variants necessitates urgent development of novel antituberculars. An im...
Autores principales: | Adams, Oliver, Deme, Justin C., Parker, Joanne L., Fowler, Philip W., Lea, Susan M., Newstead, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752444/ https://www.ncbi.nlm.nih.gov/pubmed/34242558 http://dx.doi.org/10.1016/j.str.2021.06.013 |
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