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Neuronal Loss of the Glutamate Transporter GLT-1 Promotes Excitotoxic Injury in the Hippocampus

GLT-1, the major glutamate transporter in the mammalian central nervous system, is expressed in presynaptic terminals that use glutamate as a neurotransmitter, in addition to astrocytes. It is widely assumed that glutamate homeostasis is regulated primarily by glutamate transporters expressed in ast...

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Detalles Bibliográficos
Autores principales: Rimmele, Theresa S., Li, Shaomin, Andersen, Jens Velde, Westi, Emil W., Rotenberg, Alexander, Wang, Jianlin, Aldana, Blanca Irene, Selkoe, Dennis J., Aoki, Chiye J., Dulla, Chris G., Rosenberg, Paul Allen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752461/
https://www.ncbi.nlm.nih.gov/pubmed/35035352
http://dx.doi.org/10.3389/fncel.2021.788262