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Spread of variants of epidemic disease based on the microscopic numerical simulations on networks

Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of variants. Assume that a small number of individuals infected with...

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Autores principales: Okabe, Yutaka, Shudo, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752609/
https://www.ncbi.nlm.nih.gov/pubmed/35017624
http://dx.doi.org/10.1038/s41598-021-04520-0
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author Okabe, Yutaka
Shudo, Akira
author_facet Okabe, Yutaka
Shudo, Akira
author_sort Okabe, Yutaka
collection PubMed
description Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of variants. Assume that a small number of individuals infected with the variant are added to widespread infection with the original virus. When a highly infectious variant that is more transmissible than the original lineage is added, the variant spreads quickly to the wide space. On the other hand, if the infectivity is about the same as that of the original virus, the infection will not spread. The rate of spread is not linear as a function of the infection strength but increases non-linearly. This cannot be explained by the compartmental model of epidemiology but can be understood in terms of the dynamic absorbing state known from the contact process.
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spelling pubmed-87526092022-01-13 Spread of variants of epidemic disease based on the microscopic numerical simulations on networks Okabe, Yutaka Shudo, Akira Sci Rep Article Viruses constantly undergo mutations with genomic changes. The propagation of variants of viruses is an interesting problem. We perform numerical simulations of the microscopic epidemic model based on network theory for the spread of variants. Assume that a small number of individuals infected with the variant are added to widespread infection with the original virus. When a highly infectious variant that is more transmissible than the original lineage is added, the variant spreads quickly to the wide space. On the other hand, if the infectivity is about the same as that of the original virus, the infection will not spread. The rate of spread is not linear as a function of the infection strength but increases non-linearly. This cannot be explained by the compartmental model of epidemiology but can be understood in terms of the dynamic absorbing state known from the contact process. Nature Publishing Group UK 2022-01-11 /pmc/articles/PMC8752609/ /pubmed/35017624 http://dx.doi.org/10.1038/s41598-021-04520-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Okabe, Yutaka
Shudo, Akira
Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title_full Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title_fullStr Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title_full_unstemmed Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title_short Spread of variants of epidemic disease based on the microscopic numerical simulations on networks
title_sort spread of variants of epidemic disease based on the microscopic numerical simulations on networks
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752609/
https://www.ncbi.nlm.nih.gov/pubmed/35017624
http://dx.doi.org/10.1038/s41598-021-04520-0
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