Cancer cell-expressed BTNL2 facilitates tumour immune escape via engagement with IL-17A-producing γδ T cells

Therapeutic blockade of the immune checkpoint proteins programmed cell death protein 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA4) has transformed cancer treatment. However, the overall response rate to these treatments is low, suggesting that immune checkpoint activation is not the only mec...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Yanyun, Peng, Qianwen, Cheng, Du, Pan, Ting, Sun, Wanwei, Wang, Heping, Ma, Xiaojian, He, Ruirui, Zhang, Huazhi, Cui, Zhihui, Feng, Xiong, Liu, Zhiqiang, Zhao, Tianxin, Hu, Wenjun, Shen, Lei, Jiang, Wenyang, Gao, Na, Martin, Bradley N., Zhang, Cun-Jin, Zhang, Zhanguo, Wang, Chenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752682/
https://www.ncbi.nlm.nih.gov/pubmed/35017553
http://dx.doi.org/10.1038/s41467-021-27936-8

Ejemplares similares

Ejemplares similares