Cargando…

The therapeutic implications of immunosuppressive tumor aerobic glycolysis

In 2011, Hanahan and Weinberg added “Deregulating Cellular Energetics” and “Avoiding Immune Destruction” to the six previous hallmarks of cancer. Since this seminal paper, there has been a growing consensus that these new hallmarks are not mutually exclusive but rather interdependent. The following...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reinfeld, Bradley I., Rathmell, W. Kimryn, Kim, Tae Kon, Rathmell, Jeffrey C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752729/ https://www.ncbi.nlm.nih.gov/pubmed/34239083 http://dx.doi.org/10.1038/s41423-021-00727-3

Ejemplares similares

Untangling ccRCC prognosis with SLINKY
por: Reinfeld, Bradley I., et al.
Publicado: (2017)

The tumor microenvironment as a metabolic barrier to effector T cells and immunotherapy
por: Lim, Aaron R, et al.
Publicado: (2020)

Genomics of chromophobe renal cell carcinoma: implications from a rare tumor for pan-cancer studies
por: Rathmell, Kimryn W., et al.
Publicado: (2015)

Modeling Clear Cell Renal Cell Carcinoma and Therapeutic Implications
por: Wolf, Melissa M., et al.
Publicado: (2020)

Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells
por: Cao, Yilin, et al.
Publicado: (2014)

CD28 costimulation drives tumor-infiltrating T cell glycolysis to promote inflammation
por: Beckermann, Kathryn E., et al.
Publicado: (2020)

HIF1α and HIF2α Exert Distinct Nutrient Preferences in Renal Cells
por: Arreola, Alexandra, et al.
Publicado: (2014)

Renal cell carcinoma
por: Jonasch, Eric, et al.
Publicado: (2014)

Systematic Review: ClearCode 34 – A Validated Prognostic Signature in Clear Cell Renal Cell Carcinoma (ccRCC)
por: Ghatalia, Pooja, et al.
Publicado: (2018)

Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer
por: Glass, Evan B., et al.
Publicado: (2022)

COVID-19 impact on early career investigators: a call for action
por: Levine, Ross L., et al.
Publicado: (2020)

Integrative computational immunogenomic profiling of cortisol‐secreting adrenocortical carcinoma
por: Baechle, Jordan J., et al.
Publicado: (2021)

Pleiotropic Effects of the Trichloroethylene-Associated P81S VHL Mutation on Metabolism, Apoptosis, and ATM-Mediated DNA Damage Response
por: DeSimone, Michelle C., et al.
Publicado: (2013)

VHL Type 2B Mutations Retain VBC Complex Form and Function
por: Hacker, Kathryn E., et al.
Publicado: (2008)

Commitment to Aerobic Glycolysis Sustains Immunosuppression of Human Mesenchymal Stem Cells
por: Liu, Yijun, et al.
Publicado: (2018)

Metabolism of parathyroid organoids
por: Sekhar, Konjeti R., et al.
Publicado: (2023)

Emerging Roles and Therapeutic Interventions of Aerobic Glycolysis in Glioma
por: Han, Wei, et al.
Publicado: (2020)

Tumor Energy Metabolism and Potential of 3-Bromopyruvate as an Inhibitor of Aerobic Glycolysis: Implications in Tumor Treatment
por: Fan, Tengjiao, et al.
Publicado: (2019)

Apoptolidin family glycomacrolides target leukemia through inhibition of ATP synthase
por: Reisman, Benjamin J., et al.
Publicado: (2022)

The sweet trap in tumors: aerobic glycolysis and potential targets for therapy
por: Yu, Li, et al.
Publicado: (2016)

Metabolic regulation of Akt: roles reversed
por: Coloff, Jonathan L., et al.
Publicado: (2006)

Activated lymphocytes as a metabolic model for carcinogenesis
por: Macintyre, Andrew N, et al.
Publicado: (2013)

A Case Report of Severe Type B Lactic Acidosis Following First Dose of Nivolumab in a VHL-Mutated Metastatic Renal Cell Carcinoma
por: Nakajima, Erica, et al.
Publicado: (2017)

Oncogenic virus-induced aerobic glycolysis and tumorigenesis
por: Yu, Li, et al.
Publicado: (2018)

Micromanaging aerobic respiration and glycolysis in cancer cells
por: Orang, Ayla V., et al.
Publicado: (2019)

Clinical and immunologic correlates of response to PD-1 blockade in a patient with metastatic renal medullary carcinoma
por: Beckermann, Kathryn E., et al.
Publicado: (2017)

Glycolysis-dependent histone deacetylase 4 degradation regulates inflammatory cytokine production
por: Wang, Bin, et al.
Publicado: (2014)

WWOX loss activates aerobic glycolysis
por: Abu-Remaileh, Muhannad, et al.
Publicado: (2014)

Aerobic Glycolysis: Beyond Proliferation
por: Jones, William, et al.
Publicado: (2015)

Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma
por: Feng, Jiao, et al.
Publicado: (2020)

Molecular determinants for α-tubulin methylation by SETD2
por: Kearns, Sarah, et al.
Publicado: (2021)

Racial difference in histologic subtype of renal cell carcinoma
por: Olshan, Andrew F, et al.
Publicado: (2013)

Microenvironmental influences on T cell immunity in cancer and inflammation
por: Heintzman, Darren R., et al.
Publicado: (2022)

Aerobic glycolysis, motility, and cytoskeletal remodeling
por: Verdone, James E, et al.
Publicado: (2015)

Proton export upregulates aerobic glycolysis
por: Russell, Shonagh, et al.
Publicado: (2022)

A global view of the aspiring physician-scientist
por: Williams, Christopher S, et al.
Publicado: (2022)

Glutathione peroxidase 4 inhibition induces ferroptosis and mTOR pathway suppression in thyroid cancer
por: Sekhar, Konjeti R., et al.
Publicado: (2022)

The influence of circadian rhythms and aerobic glycolysis in autism spectrum disorder
por: Vallée, Alexandre, et al.
Publicado: (2020)

Ultrasound Molecular Imaging of VEGFR-2 in Clear-Cell Renal Cell Carcinoma Tracks Disease Response to Antiangiogenic and Notch-Inhibition Therapy
por: Rojas, Juan D., et al.
Publicado: (2018)

Brain aerobic glycolysis and resilience in Alzheimer disease
por: Goyal, Manu S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_pabs71og16i52i1gle075o7nma