Cargando…
An anionic ligand snap-locks a long-range interaction in a magnesium-folded riboswitch
The archetypical transcriptional crcB fluoride riboswitch from Bacillus cereus is an intricately structured non-coding RNA element enhancing gene expression in response to toxic levels of fluoride. Here, we used single molecule FRET to uncover three dynamically interconverting conformations appearin...
Autores principales: | Yadav, Rajeev, Widom, Julia R., Chauvier, Adrien, Walter, Nils G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752731/ https://www.ncbi.nlm.nih.gov/pubmed/35017489 http://dx.doi.org/10.1038/s41467-021-27827-y |
Ejemplares similares
-
Crystal structure and ligand-induced folding of the SAM/SAH riboswitch
por: Huang, Lin, et al.
Publicado: (2020) -
Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch
por: Hu, Guodong, et al.
Publicado: (2023) -
Magnesium ions mediate ligand binding and conformational transition of the SAM/SAH riboswitch
por: Hu, Guodong, et al.
Publicado: (2023) -
Observation of long-range tertiary interactions during ligand binding by the TPP riboswitch aptamer
por: Duesterberg, Van K, et al.
Publicado: (2015) -
Single transcriptional and translational preQ(1) riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure
por: Suddala, Krishna C., et al.
Publicado: (2013)