A propolis-derived small molecule ameliorates metabolic syndrome in obese mice by targeting the CREB/CRTC2 transcriptional complex

The molecular targets and mechanisms of propolis ameliorating metabolic syndrome are not fully understood. Here, we report that Brazilian green propolis reduces fasting blood glucose levels in obese mice by disrupting the formation of CREB/CRTC2 transcriptional complex, a key regulator of hepatic gl...

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Detalles Bibliográficos
Autores principales: Chen, Yaqiong, Wang, Jiang, Wang, Yibing, Wang, Pengfei, Zhou, Zan, Wu, Rong, Xu, Qian, You, Hanyun, Liu, Yaxin, Wang, Lei, Zhou, Lingqin, Wu, Yuting, Hu, Lihong, Liu, Hong, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752738/
https://www.ncbi.nlm.nih.gov/pubmed/35017472
http://dx.doi.org/10.1038/s41467-021-27533-9

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