A new transgene mouse model using an extravesicular EGFP tag enables affinity isolation of cell-specific extracellular vesicles

The in vivo function of cell-derived extracellular vesicles (EVs) is challenging to establish since cell-specific EVs are difficult to isolate and differentiate. We, therefore, created an EV reporter using truncated CD9 to display enhanced green fluorescent protein (EGFP) on the EV surface. CD9truc-...

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Detalles Bibliográficos
Autores principales: Nørgård, Mikkel Ø., Steffensen, Lasse B., Hansen, Didde R., Füchtbauer, Ernst-Martin, Engelund, Morten B., Dimke, Henrik, Andersen, Ditte C., Svenningsen, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752749/
https://www.ncbi.nlm.nih.gov/pubmed/35017633
http://dx.doi.org/10.1038/s41598-021-04512-0

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