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Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection

Despite successful combination antiretroviral therapy (cART), persistent low-grade immune activation together with inflammation and toxic antiretroviral drugs can lead to long-lasting metabolic flexibility and adaptation in people living with HIV (PLWH). Our study investigated alterations in the pla...

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Detalles Bibliográficos
Autores principales: Mikaeloff, Flora, Svensson Akusjärvi, Sara, Ikomey, George Mondinde, Krishnan, Shuba, Sperk, Maike, Gupta, Soham, Magdaleno, Gustavo Daniel Vega, Escós, Alejandra, Lyonga, Emilia, Okomo, Marie Claire, Tagne, Claude Tayou, Babu, Hemalatha, Lorson, Christian L., Végvári, Ákos, Banerjea, Akhil C., Kele, Julianna, Hanna, Luke Elizabeth, Singh, Kamal, de Magalhães, João Pedro, Benfeitas, Rui, Neogi, Ujjwal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752762/
https://www.ncbi.nlm.nih.gov/pubmed/35017663
http://dx.doi.org/10.1038/s42003-021-02985-3