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IFNγ signaling integrity in colorectal cancer immunity and immunotherapy

The majority of colorectal cancer patients are not responsive to immune checkpoint blockade (ICB). The interferon gamma (IFNγ) signaling pathway drives spontaneous and ICB-induced antitumor immunity. In this review, we summarize recent advances in the epigenetic, genetic, and functional integrity of...

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Detalles Bibliográficos
Autores principales:	Du, Wan, Frankel, Timothy L., Green, Michael, Zou, Weiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752802/ https://www.ncbi.nlm.nih.gov/pubmed/34385592 http://dx.doi.org/10.1038/s41423-021-00735-3

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