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Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer

The colonic mucus layer is organized as a two-layered system providing a physical barrier against pathogens and simultaneously harboring the commensal flora. The factors contributing to the organization of this gel network are not well understood. In this study, the impact of transglutaminase activi...

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Detalles Bibliográficos
Autores principales:	Sharpen, Jack D. A., Dolan, Brendan, Nyström, Elisabeth E. L., Birchenough, George M. H., Arike, Liisa, Martinez-Abad, Beatriz, Johansson, Malin E. V., Hansson, Gunnar C., Recktenwald, Christian V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752817/ https://www.ncbi.nlm.nih.gov/pubmed/35017479 http://dx.doi.org/10.1038/s41467-021-27743-1

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