Elevated microglial oxidative phosphorylation and phagocytosis stimulate post-stroke brain remodeling and cognitive function recovery in mice

New research shows that disease-associated microglia in neurodegenerative brains present features of elevated phagocytosis, lysosomal functions, and lipid metabolism, which benefit brain repair. The underlying mechanisms remain poorly understood. Intracellular pH (pH(i)) is important for regulating...

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Detalles Bibliográficos
Autores principales: Song, Shanshan, Yu, Lauren, Hasan, Md Nabiul, Paruchuri, Satya S., Mullett, Steven J., Sullivan, Mara L. G., Fiesler, Victoria M., Young, Cullen B., Stolz, Donna B., Wendell, Stacy G., Sun, Dandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752825/
https://www.ncbi.nlm.nih.gov/pubmed/35017668
http://dx.doi.org/10.1038/s42003-021-02984-4

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