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Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies

Influenza A viruses cause seasonal epidemics and global pandemics, representing a considerable burden to healthcare systems. Central to the replication cycle of influenza viruses is the viral RNA-dependent RNA polymerase which transcribes and replicates the viral RNA genome. The polymerase undergoes...

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Detalles Bibliográficos
Autores principales:	Keown, Jeremy R., Zhu, Zihan, Carrique, Loïc, Fan, Haitian, Walker, Alexander P., Serna Martin, Itziar, Pardon, Els, Steyaert, Jan, Fodor, Ervin, Grimes, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752864/ https://www.ncbi.nlm.nih.gov/pubmed/35017564 http://dx.doi.org/10.1038/s41467-021-27950-w

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