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Obstructive hydrocephalus and intracerebral mass secondary to Epicoccumnigrum

Here we report a case of a 14-week-old girl with a history of intrauterine drug exposure and hypoxic ischemic encephalopathy secondary to cardiac arrest requiring prolonged resuscitation at birth presented with irritability and a bulging anterior fontanelle. After neurosurgical resection, pathologic...

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Detalles Bibliográficos
Autores principales: Charron, Taylor L., Gill, Michelle A., Filkins, Laura M., Rajaram, Veena, Wysocki, Christian A., Whittemore, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752875/
https://www.ncbi.nlm.nih.gov/pubmed/35036296
http://dx.doi.org/10.1016/j.mmcr.2022.01.002
Descripción
Sumario:Here we report a case of a 14-week-old girl with a history of intrauterine drug exposure and hypoxic ischemic encephalopathy secondary to cardiac arrest requiring prolonged resuscitation at birth presented with irritability and a bulging anterior fontanelle. After neurosurgical resection, pathologic examination showed fungal hyphae, and Epicoccum nigrum was detected by fungal PCR and sequencing. To our knowledge, this is the first reported case of a central nervous system infection due to Epicoccum nigrum.