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Correlation-based and feature-driven mutation signature analyses to identify genetic features associated with DNA mutagenic processes in cancer genomes

Mutation signatures represent unique sequence footprints of somatic mutations resulting from specific DNA mutagenic and repair processes. However, their causal associations and the potential utility for genome research remain largely unknown. In this study, we performed PanCancer-scale correlative a...

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Detalles Bibliográficos
Autores principales: Jeong, Hye Young, Yoo, Jinseon, Kim, Hyunwoo, Kim, Tae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korea Genome Organization 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752981/
https://www.ncbi.nlm.nih.gov/pubmed/35172473
http://dx.doi.org/10.5808/gi.21047

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