Cargando…

Knockdown of vps54 aggravates tamoxifen-induced cytotoxicity in fission yeast

Tamoxifen (TAM) is an anticancer drug used to treat estrogen receptor (ER)‒positive breast cancer. However, its ER-independent cytotoxic and antifungal activities have prompted debates on its mechanism of action. To achieve a better understanding of the ER-independent antifungal action mechanisms of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Sol, Nam, Miyoung, Lee, Ah-Reum, Baek, Seung-Tae, Kim, Min Jung, Kim, Ju Seong, Kong, Andrew Hyunsoo, Lee, Minho, Lee, Sook-Jeong, Kim, Seon-Young, Kim, Dong-Uk, Hoe, Kwang-Lae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korea Genome Organization 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8752990/ https://www.ncbi.nlm.nih.gov/pubmed/35172472 http://dx.doi.org/10.5808/gi.21049

Ejemplares similares

Editor’s Highlight: A Genome-wide Screening of Target Genes Against Silver Nanoparticles in Fission Yeast
por: Lee, Ah-Reum, et al.
Publicado: (2018)

Optimization of a microarray for fission yeast
por: Kim, Dong-Uk, et al.
Publicado: (2019)

Systematic Target Screening Revealed That Tif302 Could Be an Off-Target of the Antifungal Terbinafine in Fission Yeast
por: Lee, Sol, et al.
Publicado: (2021)

Mutation Analysis of Synthetic DNA Barcodes in a Fission Yeast Gene Deletion Library by Sanger Sequencing
por: Lee, Minho, et al.
Publicado: (2018)

VPS54 and the wobbler mouse
por: Schmitt-John, Thomas
Publicado: (2015)

Transactivation of bad by vorinostat-induced acetylated p53 enhances doxorubicin-induced cytotoxicity in cervical cancer cells
por: Lee, Sook-Jeong, et al.
Publicado: (2014)

NQO1 Deficiency Aggravates Renal Injury by Dysregulating Vps34/ATG14L Complex during Autophagy Initiation in Diabetic Nephropathy
por: Hong, Geum-Lan, et al.
Publicado: (2021)

CSNK1G2 differently sensitizes tamoxifen-induced decrease in PI3K/AKT/mTOR/S6K and ERK signaling according to the estrogen receptor existence in breast cancer cells
por: Nguyen Hoang, Anh Thu, et al.
Publicado: (2021)

Vps54 Regulates Lifespan and Locomotor Behavior in Adult Drosophila melanogaster
por: Wilkinson, Emily C., et al.
Publicado: (2021)

A genome-wide resource of cell cycle and cell shape genes of fission yeast
por: Hayles, Jacqueline, et al.
Publicado: (2013)

Genome-wide functional analysis using the barcode sequence alignment and statistical analysis (Barcas) tool
por: Mun, Jihyeob, et al.
Publicado: (2016)

miRNAs involved in LY6K and estrogen receptor α contribute to tamoxifen-susceptibility in breast cancer
por: Kim, Ye Sol, et al.
Publicado: (2016)

Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis
por: Choi, Seon-A, et al.
Publicado: (2018)

Genome-Wide Screen of Genes Required for Caffeine Tolerance in Fission Yeast
por: Calvo, Isabel A., et al.
Publicado: (2009)

Mitochondrial Dysfunction Increases Oxidative Stress and Decreases Chronological Life Span in Fission Yeast
por: Zuin, Alice, et al.
Publicado: (2008)

Variations in plasma concentrations of tamoxifen metabolites and the effects of genetic polymorphisms on tamoxifen metabolism in Korean patients with breast cancer
por: Woo, Hye In, et al.
Publicado: (2017)

Inhibition of STAT3 enhances sensitivity to tamoxifen in tamoxifen-resistant breast cancer cells
por: Moon, Seo Yun, et al.
Publicado: (2021)

The Author's Response: Assessment of Breast Cancer Patients’ Knowledge and Decisional Conflict Regarding Tamoxifen Use
por: Kim, Se Ik, et al.
Publicado: (2016)

Loss of Vps54 Function Leads to Vesicle Traffic Impairment, Protein Mis-Sorting and Embryonic Lethality
por: Karlsson, Páll, et al.
Publicado: (2013)

Assessment of Breast Cancer Patients' Knowledge and Decisional Conflict Regarding Tamoxifen Use
por: Kim, Se Ik, et al.
Publicado: (2015)

The Fission Yeast GATA Factor, Gaf1, Modulates Sexual Development via Direct Down-Regulation of ste11(+) Expression in Response to Nitrogen Starvation
por: Kim, Lila, et al.
Publicado: (2012)

Intermittent Hypoxia Can Aggravate Motor Neuronal Loss and Cognitive Dysfunction in ALS Mice
por: Kim, Sung-Min, et al.
Publicado: (2013)

8-Methoxypsoralen Induces Apoptosis by Upregulating p53 and Inhibits Metastasis by Downregulating MMP-2 and MMP-9 in Human Gastric Cancer Cells
por: Choi, Eun Kyoung, et al.
Publicado: (2023)

Variceal bleeding is aggravated by portal venous invasion of hepatocellular carcinoma: a matched nested case-control study
por: Lim, Jihye, et al.
Publicado: (2021)

LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation
por: Ho, Dong Hwan, et al.
Publicado: (2018)

Risk of fatty liver after long-term use of tamoxifen in patients with breast cancer
por: Yoo, Jeong-Ju, et al.
Publicado: (2020)

Factors associated with late recurrence after completion of 5-year adjuvant tamoxifen in estrogen receptor positive breast cancer
por: Lee, Eun-Shin, et al.
Publicado: (2016)

The effect of tamoxifen therapy on the endometrium and ovarian cyst formation in patients with breast cancer
por: Lee, Seul, et al.
Publicado: (2018)

Does Rapid Eye Movement Sleep Aggravate Obstructive Sleep Apnea?
por: Kim, Sung Hee, et al.
Publicado: (2019)

Estimating the Risks and Benefits of Tamoxifen for Prophylactic Breast Cancer Chemoprevention in Korea
por: Kim, Dong Uk, et al.
Publicado: (2012)

Cholesterol-Induced Non-Alcoholic Fatty Liver Disease and Atherosclerosis Aggravated by Systemic Inflammation
por: Kim, Eung Ju, et al.
Publicado: (2014)

Vps54 regulates Drosophila neuromuscular junction development and interacts genetically with Rab7 to control composition of the postsynaptic density
por: Patel, Prajal H., et al.
Publicado: (2020)

Mitochondrial fission, integrity and completion of mitophagy require separable functions of Vps13D in Drosophila neurons
por: Insolera, Ryan, et al.
Publicado: (2021)

Survival Outcome of Combined GnRH Agonist and Tamoxifen Is Comparable to That of Sequential Adriamycin and Cyclophosphamide Chemotherapy Plus Tamoxifen in Premenopausal Patients with Lymph-Node–Negative, Hormone-Responsive, HER2-Negative, T1-T2 Breast Cancer
por: Sohn, Guiyun, et al.
Publicado: (2016)

Aggravation of Dysphagia Aortica After Wearing the Abdominal Binder
por: Park, Seon-Young, et al.
Publicado: (2010)

Mitoribosomal defects aggravate liver cancer via aberrant glycolytic flux and T cell exhaustion
por: Song, Byong-Sop, et al.
Publicado: (2022)

Stratifin (SFN) regulates lung cancer progression via nucleating the Vps34‐BECN1‐TRAF6 complex for autophagy induction
por: Kim, Ji Young, et al.
Publicado: (2022)

Endometrial polyp surveillance in premenopausal breast cancer patients using tamoxifen
por: Jeon, Se Jeong, et al.
Publicado: (2017)

Mesoscopic Mapping of Visual Pathway in a Female 5XFAD Mouse Model of Alzheimer’s Disease
por: Nam, Yunkwon, et al.
Publicado: (2022)

mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes
por: Sadler, Jessica B A, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_a4gl5pgg0jgooc3ifs7veqd9tb