Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity

We present a case of a patient with chronic Q fever who presented with digital necrosis, autoamputations, and positive anticentromere antibody, mimicking a scleroderma vasculopathy or thromboangiitis obliterans. Coxiella burnetii infection has long been associated with the presence of autoantibodies...

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Autores principales: Shepard, Zachary, Skorupa, Tara, Espinoza, Leigh, Erlandson, Kristine, Damioli, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753030/
https://www.ncbi.nlm.nih.gov/pubmed/35028337
http://dx.doi.org/10.1093/ofid/ofab637
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author Shepard, Zachary
Skorupa, Tara
Espinoza, Leigh
Erlandson, Kristine
Damioli, Laura
author_facet Shepard, Zachary
Skorupa, Tara
Espinoza, Leigh
Erlandson, Kristine
Damioli, Laura
author_sort Shepard, Zachary
collection PubMed
description We present a case of a patient with chronic Q fever who presented with digital necrosis, autoamputations, and positive anticentromere antibody, mimicking a scleroderma vasculopathy or thromboangiitis obliterans. Coxiella burnetii infection has long been associated with the presence of autoantibodies and autoimmune phenomena including vasculitis. Clinicians should consider Q fever testing in patients with new-onset autoimmune diseases or autoantibodies and appropriate exposure histories.
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spelling pubmed-87530302022-01-12 Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity Shepard, Zachary Skorupa, Tara Espinoza, Leigh Erlandson, Kristine Damioli, Laura Open Forum Infect Dis Brief Report We present a case of a patient with chronic Q fever who presented with digital necrosis, autoamputations, and positive anticentromere antibody, mimicking a scleroderma vasculopathy or thromboangiitis obliterans. Coxiella burnetii infection has long been associated with the presence of autoantibodies and autoimmune phenomena including vasculitis. Clinicians should consider Q fever testing in patients with new-onset autoimmune diseases or autoantibodies and appropriate exposure histories. Oxford University Press 2021-12-16 /pmc/articles/PMC8753030/ /pubmed/35028337 http://dx.doi.org/10.1093/ofid/ofab637 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Shepard, Zachary
Skorupa, Tara
Espinoza, Leigh
Erlandson, Kristine
Damioli, Laura
Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title_full Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title_fullStr Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title_full_unstemmed Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title_short Coxiella burnetii Infection Associated With Thromboangiitis Obliterans–like Phenomena With Digital Autoamputation: A Case Report and Review of Q Fever–Associated Autoimmunity
title_sort coxiella burnetii infection associated with thromboangiitis obliterans–like phenomena with digital autoamputation: a case report and review of q fever–associated autoimmunity
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753030/
https://www.ncbi.nlm.nih.gov/pubmed/35028337
http://dx.doi.org/10.1093/ofid/ofab637
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