Prognostic impact of CEBPA bZIP domain mutation in acute myeloid leukemia

Mutations of CCAAT/enhancer–binding protein alpha (CEBPAmu) are found in 10% to 15% of de novo acute myeloid leukemia (AML) cases. Double-mutated CEBPA (CEBPAdm) is associated with a favorable prognosis; however, single-mutated CEBPA (CEBPAsm) does not seem to improve prognosis. We investigated CEBP...

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Detalles Bibliográficos
Autores principales: Wakita, Satoshi, Sakaguchi, Masahiro, Oh, Iekuni, Kako, Shinichi, Toya, Takashi, Najima, Yuho, Doki, Noriko, Kanda, Junya, Kuroda, Junya, Mori, Shinichiro, Satake, Atsushi, Usuki, Kensuke, Ueki, Toshimitsu, Uoshima, Nobuhiko, Kobayashi, Yutaka, Kawata, Eri, Tajika, Kenji, Nagao, Yuhei, Shono, Katsuhiro, Shibusawa, Motoharu, Tadokoro, Jiro, Kayamori, Kensuke, Hagihara, Masao, Uchiyama, Hitoji, Uchida, Naoyuki, Kubota, Yasushi, Kimura, Shinya, Nagoshi, Hisao, Ichinohe, Tatsuo, Kurosawa, Saiko, Motomura, Sayuri, Hashimoto, Akiko, Muto, Hideharu, Sato, Eriko, Ogata, Masao, Mitsuhashi, Kenjiro, Ando, Jun, Marumo, Atsushi, Omori, Ikuko, Fujiwara, Yusuke, Terada, Kazuki, Yui, Shunsuke, Arai, Kunihito, Kitano, Tomoaki, Miyata, Miho, Kurosawa, Akiyo, Mizoguchi, Ayumi, Komatsu, Norio, Fukuda, Takahiro, Ohashi, Kazuteru, Kanda, Yoshinobu, Inokuchi, Koiti, Yamaguchi, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Myeloid Neoplasia
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753195/
https://www.ncbi.nlm.nih.gov/pubmed/34448807
http://dx.doi.org/10.1182/bloodadvances.2021004292

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