KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia

Epigenetic histone modifiers are key regulators of cell fate decisions in normal and malignant hematopoiesis. Their enzymatic activities are of particular significance as putative therapeutic targets in leukemia. In contrast, less is known about the contextual role in which those enzymatic activitie...

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Detalles Bibliográficos
Autores principales: Arede, Liliana, Foerner, Elena, Wind, Selinde, Kulkarni, Rashmi, Domingues, Ana Filipa, Giotopoulos, George, Kleinwaechter, Svenja, Mollenhauer-Starkl, Maximilian, Davison, Holly, Chandru, Aditya, Asby, Ryan, Samarista, Ralph, Gupta, Shikha, Forte, Dorian, Curti, Antonio, Scheer, Elisabeth, Huntly, Brian J. P., Tora, Laszlo, Pina, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2022
Materias:
Hematopoiesis and Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753207/
https://www.ncbi.nlm.nih.gov/pubmed/34654054
http://dx.doi.org/10.1182/bloodadvances.2020002842

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