The binding of autotaxin to integrins mediates hyperhomocysteinemia-potentiated platelet activation and thrombosis in mice and humans

Hyperhomocysteinemia (HHcy) is associated with an exaggerated platelet thrombotic response at sites of vascular injury. In this study, human medical examination showed that elevated human plasma Hcy levels correlated positively with enhanced blood coagulation and platelet activity, suggesting that h...

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Detalles Bibliográficos
Autores principales: Han, Lulu, Miao, Yutong, Zhao, Yang, Zhang, Xingzhong, Ma, Xiaolong, Du, Xing, Kong, Wei, Xu, Qingbo, Liu, Junling, Dai, Kesheng, Feng, Juan, Wang, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Thrombosis and Hemostasis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753216/
https://www.ncbi.nlm.nih.gov/pubmed/34559203
http://dx.doi.org/10.1182/bloodadvances.2021004572

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