Cargando…

Increased mitochondrial fission drives the reprogramming of fatty acid metabolism in hepatocellular carcinoma cells through suppression of Sirtuin 1

BACKGROUND: Mitochondria are dynamic organelles that constantly change their morphology through fission and fusion processes. Recently, abnormally increased mitochondrial fission has been observed in several types of cancer. However, the functional roles of increased mitochondrial fission in lipid m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Dan, Yang, Yi, Hou, Yiran, Zhao, Zifeng, Liang, Ning, Yuan, Peng, Yang, Tao, Xing, Jinliang, Li, Jibin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753313/ https://www.ncbi.nlm.nih.gov/pubmed/34981667 http://dx.doi.org/10.1002/cac2.12247

Ejemplares similares

Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways
por: Huang, Qichao, et al.
Publicado: (2016)

Investigating the role of Sirtuins in cell reprogramming
por: Shin, Jaein, et al.
Publicado: (2018)

Mitochondrial Fission Induces Glycolytic Reprogramming in Cancer-Associated Myofibroblasts, Driving Stromal Lactate Production, and Early Tumor Growth
por: Guido, Carmela, et al.
Publicado: (2012)

Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice
por: Goetzman, Eric S., et al.
Publicado: (2020)

Fructose drives mitochondrial metabolic reprogramming in podocytes via Hmgcs2-stimulated fatty acid degradation
por: Fang, Lei, et al.
Publicado: (2021)

SIK2 enhances synthesis of fatty acid and cholesterol in ovarian cancer cells and tumor growth through PI3K/Akt signaling pathway
por: Zhao, Jing, et al.
Publicado: (2020)

Down-regulation of BMAL1 by MiR-494-3p Promotes Hepatocellular Carcinoma Growth and Metastasis by Increasing GPAM-mediated Lipid Biosynthesis
por: Yang, Yi, et al.
Publicado: (2022)

Mitochondrial Sirtuins in Reproduction
por: Di Emidio, Giovanna, et al.
Publicado: (2021)

Suppressing DRP1-mediated mitochondrial fission and mitophagy increases mitochondrial apoptosis of hepatocellular carcinoma cells in the setting of hypoxia
por: Lin, Xia-Hui, et al.
Publicado: (2020)

Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma
por: Zhao, Jing, et al.
Publicado: (2019)

Sirtuin 3 Downregulation in Mycobacterium tuberculosis-Infected Macrophages Reprograms Mitochondrial Metabolism and Promotes Cell Death
por: Smulan, Lorissa J., et al.
Publicado: (2021)

Drp1-mediated mitochondrial fission promotes cell proliferation through crosstalk of p53 and NF-κB pathways in hepatocellular carcinoma
por: Zhan, Lei, et al.
Publicado: (2016)

MFN1-dependent alteration of mitochondrial dynamics drives hepatocellular carcinoma metastasis by glucose metabolic reprogramming
por: Zhang, Ze, et al.
Publicado: (2019)

Fis1 phosphorylation by Met promotes mitochondrial fission and hepatocellular carcinoma metastasis
por: Yu, Yan, et al.
Publicado: (2021)

Perspectives of Molecular Therapy-Targeted Mitochondrial Fission in Hepatocellular Carcinoma
por: Zhang, Hanwen, et al.
Publicado: (2020)

Mitochondrial fission-induced mtDNA stress promotes tumor-associated macrophage infiltration and HCC progression
por: Bao, Dengke, et al.
Publicado: (2019)

Low Expression of Phosphodiesterase 2 (PDE2A) Promotes the Progression by Regulating Mitochondrial Morphology and ATP Content and Predicts Poor Prognosis in Hepatocellular Carcinoma
por: Chen, Lin, et al.
Publicado: (2022)

Sirtuins and nonalcoholic fatty liver disease
por: Nassir, Fatiha, et al.
Publicado: (2016)

The Imbalance of Mitochondrial Fusion/Fission Drives High-Glucose-Induced Vascular Injury
por: Zheng, Yunsi, et al.
Publicado: (2021)

An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion
por: Nguyen, Tricia T, et al.
Publicado: (2022)

Protective effects of mitochondrial fission inhibition on ox-LDL induced VSMC foaming via metabolic reprogramming
por: Fang, Yijin, et al.
Publicado: (2022)

Suppression of Cpn10 Increases Mitochondrial Fission and Dysfunction in Neuroblastoma Cells
por: Park, So Jung, et al.
Publicado: (2014)

Mitochondrial fission factor (MFF) frameshift variant in Bullmastiffs with mitochondrial fission encephalopathy
por: Christen, Matthias, et al.
Publicado: (2022)

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming
por: Prieto, Javier, et al.
Publicado: (2016)

Positive feedback loop between mitochondrial fission and Notch signaling promotes survivin-mediated survival of TNBC cells
por: Chen, Li, et al.
Publicado: (2018)

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
por: Bussi, Claudio, et al.
Publicado: (2022)

Down-regulation of SLC25A20 promotes hepatocellular carcinoma growth and metastasis through suppression of fatty-acid oxidation
por: Yuan, Peng, et al.
Publicado: (2021)

The Role and Therapeutic Perspectives of Sirtuin 3 in Cancer Metabolism Reprogramming, Metastasis, and Chemoresistance
por: Zhao, QingYi, et al.
Publicado: (2022)

Sirtuins and redox signaling interplay in neurogenesis, neurodegenerative diseases, and neural cell reprogramming
por: Mormone, Elisabetta, et al.
Publicado: (2023)

Mitochondrial fission factor promotes cisplatin resistancein hepatocellular carcinoma: Mff promotes cisplatin resistance in HCC
por: Li, Xiaoliang, et al.
Publicado: (2022)

Enhanced mitochondrial fission suppresses signaling and metastasis in triple-negative breast cancer
por: Humphries, Brock A., et al.
Publicado: (2020)

Oncometabolic role of mitochondrial sirtuins in glioma patients
por: Haq, Maria Fazal Ul, et al.
Publicado: (2023)

Sirtuins in glucose and lipid metabolism
por: Ye, Xin, et al.
Publicado: (2016)

Organelle remodeling in somatic cell reprogramming
por: Liu, Yang, et al.
Publicado: (2020)

Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
por: Zwaans, Bernadette M. M., et al.
Publicado: (2014)

Tumor suppressive role of mitochondrial sirtuin 4 in induction of G2/M cell cycle arrest and apoptosis in hepatitis B virus-related hepatocellular carcinoma
por: Huang, Fung-Yu, et al.
Publicado: (2021)

Alterations in mitochondrial dynamics with age‐related Sirtuin1/Sirtuin3 deficiency impair cardiomyocyte contractility
por: Zhang, Jingwen, et al.
Publicado: (2021)

Mathematical Modeling of the Role of Mitochondrial Fusion and Fission in Mitochondrial DNA Maintenance
por: Tam, Zhi Yang, et al.
Publicado: (2013)

Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan
por: Lefevre, Sophie D, et al.
Publicado: (2015)

Inhibition of calpain reduces cell apoptosis by suppressing mitochondrial fission in acute viral myocarditis
por: Shi, Hui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_mqn0ac3socuafj1869oc7i9oe9