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Ginsenoside Rh2 reduces depression in offspring of mice with maternal toxoplasma infection during pregnancy by inhibiting microglial activation via the HMGB1/TLR4/NF-κB signaling pathway
BACKGROUND: Maternal Toxoplasma gondii (T. gondii) infection during pregnancy has been associated with various mental illnesses in the offspring. Ginsenoside Rh2 (GRh2) is a major bioactive compound obtained from ginseng that has an anti-T. gondii effect and attenuates microglial activation through...
Autores principales: | Xu, Xiang, Lu, Yu-Nan, Cheng, Jia-Hui, Lan, Hui-Wen, Lu, Jing-Mei, Jin, Guang-Nan, Xu, Guang-Hua, Jin, Cheng-Hua, Ma, Juan, Piao, Hu-Nan, Jin, Xuejun, Piao, Lian-Xun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753429/ https://www.ncbi.nlm.nih.gov/pubmed/35035240 http://dx.doi.org/10.1016/j.jgr.2021.04.003 |
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