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Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension

BACKGROUND: Hypoxic pulmonary hypertension (HPH) is a chronic progressive advanced disorder pathologically characterized by pulmonary vascular remodeling. Notch4 as a cell surface receptor is critical for vascular development. However, little is known about the role and mechanism of Notch4 in the de...

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Detalles Bibliográficos
Autores principales:	Guo, Mingzhou, Zhang, Mengzhe, Cao, Xiaopei, Fang, Xiaoyu, Li, Ke, Qin, Lu, He, Yuanzhou, Zhao, Jianping, Xu, Yongjian, Liu, Xiansheng, Li, Xiaochen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8753901/ https://www.ncbi.nlm.nih.gov/pubmed/35016680 http://dx.doi.org/10.1186/s12931-022-01927-9

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