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Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient

Patient: Female, 83-year-old Final Diagnosis: Gastrointestinal stromal tumour Symptoms: Abdominal discomfort • abdominal distension Medication: — Clinical Procedure: Colectomy • distal subtotal gastrectomy Specialty: Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Gastrointestinal stromal tum...

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Autores principales: Yeoh, Bryan Zhi Yong, Hoe, Vee Chuan, Kong, Shu Ning, Ooi, Wei Kiat, Chiew, Kar Yee, Hayati, Firdaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754006/
https://www.ncbi.nlm.nih.gov/pubmed/34992206
http://dx.doi.org/10.12659/AJCR.934492
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author Yeoh, Bryan Zhi Yong
Hoe, Vee Chuan
Kong, Shu Ning
Ooi, Wei Kiat
Chiew, Kar Yee
Hayati, Firdaus
author_facet Yeoh, Bryan Zhi Yong
Hoe, Vee Chuan
Kong, Shu Ning
Ooi, Wei Kiat
Chiew, Kar Yee
Hayati, Firdaus
author_sort Yeoh, Bryan Zhi Yong
collection PubMed
description Patient: Female, 83-year-old Final Diagnosis: Gastrointestinal stromal tumour Symptoms: Abdominal discomfort • abdominal distension Medication: — Clinical Procedure: Colectomy • distal subtotal gastrectomy Specialty: Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. CASE REPORT: We report a case of a giant GIST (25×18×8.5 cm) in an 83-year-old woman, which we believe is the largest reported GIST, in Borneo, Malaysia. She presented with gradually increasing abdominal distension with occasional discomfort on movement for 1 month. Computed tomography revealed a large multilobulated enhancing mass measuring 10×20×22 cm with no clear plane with the posterior gastric wall, duodenum, and pancreas. We performed a distal gastrectomy and transverse colon segmentectomy, as the tumor was plastered to the mesentery of the transverse colon. Despite extensive surgery, she recovered well after surgery. Due to her advanced age and the tumor size, a tyrosine kinase inhibitor was not given owing to the possibility of adverse effects. CONCLUSIONS: The management of GIST is complicated, especially for a huge GIST with local invasion. Despite the benefits of a tyrosine kinase inhibitor, the role of surgery in managing GIST is crucial, especially for patients with huge tumor size, advanced age, and local complications from the tumor.
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spelling pubmed-87540062022-01-21 Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient Yeoh, Bryan Zhi Yong Hoe, Vee Chuan Kong, Shu Ning Ooi, Wei Kiat Chiew, Kar Yee Hayati, Firdaus Am J Case Rep Articles Patient: Female, 83-year-old Final Diagnosis: Gastrointestinal stromal tumour Symptoms: Abdominal discomfort • abdominal distension Medication: — Clinical Procedure: Colectomy • distal subtotal gastrectomy Specialty: Surgery OBJECTIVE: Unusual clinical course BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract and mostly affect the stomach. The size of the tumors vary, ranging from 0.6 cm to 25.5 cm, with a median size of 6.8 cm. CASE REPORT: We report a case of a giant GIST (25×18×8.5 cm) in an 83-year-old woman, which we believe is the largest reported GIST, in Borneo, Malaysia. She presented with gradually increasing abdominal distension with occasional discomfort on movement for 1 month. Computed tomography revealed a large multilobulated enhancing mass measuring 10×20×22 cm with no clear plane with the posterior gastric wall, duodenum, and pancreas. We performed a distal gastrectomy and transverse colon segmentectomy, as the tumor was plastered to the mesentery of the transverse colon. Despite extensive surgery, she recovered well after surgery. Due to her advanced age and the tumor size, a tyrosine kinase inhibitor was not given owing to the possibility of adverse effects. CONCLUSIONS: The management of GIST is complicated, especially for a huge GIST with local invasion. Despite the benefits of a tyrosine kinase inhibitor, the role of surgery in managing GIST is crucial, especially for patients with huge tumor size, advanced age, and local complications from the tumor. International Scientific Literature, Inc. 2022-01-07 /pmc/articles/PMC8754006/ /pubmed/34992206 http://dx.doi.org/10.12659/AJCR.934492 Text en © Am J Case Rep, 2022 https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Yeoh, Bryan Zhi Yong
Hoe, Vee Chuan
Kong, Shu Ning
Ooi, Wei Kiat
Chiew, Kar Yee
Hayati, Firdaus
Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title_full Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title_fullStr Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title_full_unstemmed Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title_short Successful En Bloc Resection of Complicated Giant Stomach Gastrointestinal Stromal Tumor in an Elderly Patient
title_sort successful en bloc resection of complicated giant stomach gastrointestinal stromal tumor in an elderly patient
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754006/
https://www.ncbi.nlm.nih.gov/pubmed/34992206
http://dx.doi.org/10.12659/AJCR.934492
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