Cargando…
Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R
The limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress toward vaccine development. Previously, the DP148R gene was deleted from the genome of genotype I virulent Benin 97/1 isolate. This virus, BeninΔDP148R, induced transie...
Autores principales: | Petrovan, Vlad, Rathakrishnan, Anusyah, Islam, Muneeb, Goatley, Lynnette C., Moffat, Katy, Sanchez-Cordon, Pedro J., Reis, Ana L., Dixon, Linda K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754224/ https://www.ncbi.nlm.nih.gov/pubmed/34643433 http://dx.doi.org/10.1128/JVI.01340-21 |
Ejemplares similares
-
Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
por: Rathakrishnan, Anusyah, et al.
Publicado: (2022) -
Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge
por: Reis, Ana L., et al.
Publicado: (2017) -
Deletion of the K145R and DP148R Genes from the Virulent ASFV Georgia 2007/1 Isolate Delays the Onset, but Does Not Reduce Severity, of Clinical Signs in Infected Pigs
por: Rathakrishnan, Anusyah, et al.
Publicado: (2021) -
African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
por: Dodantenna, Niranjan, et al.
Publicado: (2022) -
Interleukin-27R Signaling Mediates Early Viral Containment and Impacts Innate and Adaptive Immunity after Chronic Lymphocytic Choriomeningitis Virus Infection
por: Harker, James A., et al.
Publicado: (2018)