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Peroxisome function relies on organelle-associated mRNA translation

Crucial metabolic functions of peroxisomes rely on a variety of peroxisomal membrane proteins (PMPs). While mRNA transcripts of PMPs were shown to be colocalized with peroxisomes, the process by which PMPs efficiently couple translation with targeting to the peroxisomal membrane remained elusive. He...

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Detalles Bibliográficos
Autores principales: Dahan, Noa, Bykov, Yury S., Boydston, Elizabeth A., Fadel, Amir, Gazi, Zohar, Hochberg-Laufer, Hodaya, Martenson, James, Denic, Vlad, Shav-Tal, Yaron, Weissman, Jonathan S., Aviram, Naama, Zalckvar, Einat, Schuldiner, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754406/
https://www.ncbi.nlm.nih.gov/pubmed/35020435
http://dx.doi.org/10.1126/sciadv.abk2141