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Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups

BACKGROUND: Valid biomarkers of fruit and vegetable (FV) intake are needed for field-based nutrition research. OBJECTIVES: To examine criterion-related validity of pressure-mediated reflection spectroscopy as a proxy measure of FV intake, using plasma carotenoids and self-reported FV and carotenoid...

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Autores principales: Jilcott Pitts, Stephanie B, Moran, Nancy E, Wu, Qiang, Harnack, Lisa, Craft, Neal E, Hanchard, Neil, Bell, Ronny, Moe, Stacey G, Johnson, Nevin, Obasohan, Justice, Carr-Manthe, Pamela L, Laska, Melissa N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754514/
https://www.ncbi.nlm.nih.gov/pubmed/34562088
http://dx.doi.org/10.1093/jn/nxab349
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author Jilcott Pitts, Stephanie B
Moran, Nancy E
Wu, Qiang
Harnack, Lisa
Craft, Neal E
Hanchard, Neil
Bell, Ronny
Moe, Stacey G
Johnson, Nevin
Obasohan, Justice
Carr-Manthe, Pamela L
Laska, Melissa N
author_facet Jilcott Pitts, Stephanie B
Moran, Nancy E
Wu, Qiang
Harnack, Lisa
Craft, Neal E
Hanchard, Neil
Bell, Ronny
Moe, Stacey G
Johnson, Nevin
Obasohan, Justice
Carr-Manthe, Pamela L
Laska, Melissa N
author_sort Jilcott Pitts, Stephanie B
collection PubMed
description BACKGROUND: Valid biomarkers of fruit and vegetable (FV) intake are needed for field-based nutrition research. OBJECTIVES: To examine criterion-related validity of pressure-mediated reflection spectroscopy as a proxy measure of FV intake, using plasma carotenoids and self-reported FV and carotenoid intake as primary and secondary criterion measures, respectively. METHODS: Healthy adults 18–65 y of age, self-identifying as African American/black (n = 61), Asian (n = 53), white (n = 70), or Hispanic (n = 29), in North Carolina and Minnesota were recruited. Skin carotenoids were assessed via pressure-mediated reflection spectroscopy (Veggie Meter), skin melanin via spectrophotometer, and total plasma carotenoid concentration by HPLC–photodiode array detection. Self-reported carotenoid and FV intake was assessed using a semiquantitative FFQ. Relations between skin carotenoids, plasma carotenoids, FV, and carotenoid intake, with differences by race or ethnicity, age, sex, weight status, cholesterol, and melanin index, were examined by bivariate correlations and adjusted multivariate linear regressions. RESULTS: The overall unadjusted correlation between skin and total plasma carotenoids was r = 0.71 and ranged from 0.64 (non-Hispanic black) to 0.80 (Hispanic). Correlations between skin carotenoids and self-reported FV intake ranged from 0.24 (non-Hispanic black) to 0.53 (non-Hispanic white), with an overall correlation of r = 0.35. In models adjusted for age, sex, racial or ethnic group, and BMI, skin carotenoids were associated with plasma carotenoids (R(2) = 0.55), FV (R(2) = 0.17), and carotenoid intake (R(2) = 0.20). For both plasma carotenoid and FV measures, associations with skin carotenoids did not vary by race, but these relations did differ by skin melanin—those with lower melanin had a lower correlation between skin and plasma carotenoids. CONCLUSIONS: Reflection spectroscopy–assessed skin carotenoids may be a reasonable alternative to measurement of plasma carotenoids, a biomarker used to approximate FV intake.
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spelling pubmed-87545142022-01-14 Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups Jilcott Pitts, Stephanie B Moran, Nancy E Wu, Qiang Harnack, Lisa Craft, Neal E Hanchard, Neil Bell, Ronny Moe, Stacey G Johnson, Nevin Obasohan, Justice Carr-Manthe, Pamela L Laska, Melissa N J Nutr Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions BACKGROUND: Valid biomarkers of fruit and vegetable (FV) intake are needed for field-based nutrition research. OBJECTIVES: To examine criterion-related validity of pressure-mediated reflection spectroscopy as a proxy measure of FV intake, using plasma carotenoids and self-reported FV and carotenoid intake as primary and secondary criterion measures, respectively. METHODS: Healthy adults 18–65 y of age, self-identifying as African American/black (n = 61), Asian (n = 53), white (n = 70), or Hispanic (n = 29), in North Carolina and Minnesota were recruited. Skin carotenoids were assessed via pressure-mediated reflection spectroscopy (Veggie Meter), skin melanin via spectrophotometer, and total plasma carotenoid concentration by HPLC–photodiode array detection. Self-reported carotenoid and FV intake was assessed using a semiquantitative FFQ. Relations between skin carotenoids, plasma carotenoids, FV, and carotenoid intake, with differences by race or ethnicity, age, sex, weight status, cholesterol, and melanin index, were examined by bivariate correlations and adjusted multivariate linear regressions. RESULTS: The overall unadjusted correlation between skin and total plasma carotenoids was r = 0.71 and ranged from 0.64 (non-Hispanic black) to 0.80 (Hispanic). Correlations between skin carotenoids and self-reported FV intake ranged from 0.24 (non-Hispanic black) to 0.53 (non-Hispanic white), with an overall correlation of r = 0.35. In models adjusted for age, sex, racial or ethnic group, and BMI, skin carotenoids were associated with plasma carotenoids (R(2) = 0.55), FV (R(2) = 0.17), and carotenoid intake (R(2) = 0.20). For both plasma carotenoid and FV measures, associations with skin carotenoids did not vary by race, but these relations did differ by skin melanin—those with lower melanin had a lower correlation between skin and plasma carotenoids. CONCLUSIONS: Reflection spectroscopy–assessed skin carotenoids may be a reasonable alternative to measurement of plasma carotenoids, a biomarker used to approximate FV intake. Oxford University Press 2021-09-25 /pmc/articles/PMC8754514/ /pubmed/34562088 http://dx.doi.org/10.1093/jn/nxab349 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the American Society for Nutrition. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions
Jilcott Pitts, Stephanie B
Moran, Nancy E
Wu, Qiang
Harnack, Lisa
Craft, Neal E
Hanchard, Neil
Bell, Ronny
Moe, Stacey G
Johnson, Nevin
Obasohan, Justice
Carr-Manthe, Pamela L
Laska, Melissa N
Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title_full Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title_fullStr Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title_full_unstemmed Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title_short Pressure-Mediated Reflection Spectroscopy Criterion Validity as a Biomarker of Fruit and Vegetable Intake: A 2-Site Cross-Sectional Study of 4 Racial or Ethnic Groups
title_sort pressure-mediated reflection spectroscopy criterion validity as a biomarker of fruit and vegetable intake: a 2-site cross-sectional study of 4 racial or ethnic groups
topic Nutrient Physiology, Metabolism, and Nutrient-Nutrient Interactions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754514/
https://www.ncbi.nlm.nih.gov/pubmed/34562088
http://dx.doi.org/10.1093/jn/nxab349
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