Super resolution microscopy reveals how elongating RNA polymerase II and nascent RNA interact with nucleosome clutches

Transcription and genome architecture are interdependent, but it is still unclear how nucleosomes in the chromatin fiber interact with nascent RNA, and which is the relative nuclear distribution of these RNAs and elongating RNA polymerase II (RNAP II). Using super-resolution (SR) microscopy, we visu...

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Detalles Bibliográficos
Autores principales: Castells-Garcia, Alvaro, Ed-daoui, Ilyas, González-Almela, Esther, Vicario, Chiara, Ottestrom, Jason, Lakadamyali, Melike, Neguembor, Maria Victoria, Cosma, Maria Pia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754629/
https://www.ncbi.nlm.nih.gov/pubmed/34929735
http://dx.doi.org/10.1093/nar/gkab1215

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