Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei

Loss of genome stability leads to reduced fitness, fertility and a high mutation rate. Therefore, the genome is guarded by the pathways monitoring its integrity and neutralizing DNA lesions. To analyze the mechanism of DNA damage induction by cytidine analog zebularine, we performed a forward-direct...

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Detalles Bibliográficos
Autores principales: Prochazkova, Klara, Finke, Andreas, Tomaštíková, Eva Dvořák, Filo, Jaroslav, Bente, Heinrich, Dvořák, Petr, Ovečka, Miroslav, Šamaj, Jozef, Pecinka, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754632/
https://www.ncbi.nlm.nih.gov/pubmed/34904670
http://dx.doi.org/10.1093/nar/gkab1218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754632/
https://www.ncbi.nlm.nih.gov/pubmed/34904670
http://dx.doi.org/10.1093/nar/gkab1218

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