Cargando…

Zebularine induces enzymatic DNA–protein crosslinks in 45S rDNA heterochromatin of Arabidopsis nuclei

Loss of genome stability leads to reduced fitness, fertility and a high mutation rate. Therefore, the genome is guarded by the pathways monitoring its integrity and neutralizing DNA lesions. To analyze the mechanism of DNA damage induction by cytidine analog zebularine, we performed a forward-direct...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prochazkova, Klara, Finke, Andreas, Tomaštíková, Eva Dvořák, Filo, Jaroslav, Bente, Heinrich, Dvořák, Petr, Ovečka, Miroslav, Šamaj, Jozef, Pecinka, Ales
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754632/ https://www.ncbi.nlm.nih.gov/pubmed/34904670 http://dx.doi.org/10.1093/nar/gkab1218

Ejemplares similares

Rapamycin increases rDNA stability by enhancing association of Sir2 with rDNA in Saccharomyces cerevisiae
por: Ha, Cheol Woong, et al.
Publicado: (2011)

A DYRK1B-dependent pathway suppresses rDNA transcription in response to DNA damage
por: Dong, Chao, et al.
Publicado: (2021)

SMC5/6 complex-mediated SUMOylation stimulates DNA–protein cross-link repair in Arabidopsis
por: Dvořák Tomaštíková, Eva, et al.
Publicado: (2023)

DNA-dependent protease activity of human Spartan facilitates replication of DNA–protein crosslink-containing DNA
por: Mórocz, Mónika, et al.
Publicado: (2017)

Crosslinking of DNA repair and replication proteins to DNA in cells treated with 6-thioguanine and UVA
por: Gueranger, Quentin, et al.
Publicado: (2011)

The structure and duplex context of DNA interstrand crosslinks affects the activity of DNA polymerase η
por: Roy, Upasana, et al.
Publicado: (2016)

Bypass of DNA interstrand crosslinks by a Rev1–DNA polymerase ζ complex
por: Bezalel-Buch, Rachel, et al.
Publicado: (2020)

Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases
por: Ho, The Vinh, et al.
Publicado: (2011)

FANCM interacts with PCNA to promote replication traverse of DNA interstrand crosslinks
por: Rohleder, Florian, et al.
Publicado: (2016)

RNAi and Ino80 complex control rate limiting translocation step that moves rDNA to eroding telomeres
por: Apte, Manasi S, et al.
Publicado: (2021)

CSB interacts with SNM1A and promotes DNA interstrand crosslink processing
por: Iyama, Teruaki, et al.
Publicado: (2015)

The role of SLX4 and its associated nucleases in DNA interstrand crosslink repair
por: Hoogenboom, Wouter S, et al.
Publicado: (2019)

The β-1,3-glucanosyltransferase Gas1 regulates Sir2-mediated rDNA stability in Saccharomyces cerevisiae
por: Ha, Cheol Woong, et al.
Publicado: (2014)

More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance
por: Saka, Kimiko, et al.
Publicado: (2016)

Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin
por: Lan, Li, et al.
Publicado: (2014)

Mismatch repair and nucleotide excision repair proteins cooperate in the recognition of DNA interstrand crosslinks
por: Zhao, Junhua, et al.
Publicado: (2009)

HMGB1 interacts with XPA to facilitate the processing of DNA interstrand crosslinks in human cells
por: Mukherjee, Anirban, et al.
Publicado: (2016)

Systematic analysis of DNA crosslink repair pathways during development and aging in Caenorhabditis elegans
por: Wilson, David M., et al.
Publicado: (2017)

HSF2BP negatively regulates homologous recombination in DNA interstrand crosslink repair
por: Sato, Koichi, et al.
Publicado: (2020)

Mycobacterial helicase Lhr abets resistance to DNA crosslinking agents mitomycin C and cisplatin
por: Warren, Garrett M, et al.
Publicado: (2023)

A ubiquitin switch controls autocatalytic inactivation of the DNA–protein crosslink repair protease SPRTN
por: Zhao, Shubo, et al.
Publicado: (2020)

DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin
por: Jakob, Burkhard, et al.
Publicado: (2011)

BRCC36A is epistatic to BRCA1 in DNA crosslink repair and homologous recombination in Arabidopsis thaliana
por: Block-Schmidt, Astrid S., et al.
Publicado: (2011)

The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81
por: Herrmann, Natalie J., et al.
Publicado: (2015)

The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair
por: Rosado, Ivan V., et al.
Publicado: (2009)

Identification of a novel structure-specific endonuclease AziN that contributes to the repair of azinomycin B-mediated DNA interstrand crosslinks
por: Chen, Xiaorong, et al.
Publicado: (2020)

A clickable melphalan for monitoring DNA interstrand crosslink accumulation and detecting ICL repair defects in Fanconi anemia patient cells
por: Berrada, Sara, et al.
Publicado: (2023)

Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin
por: Casas-Delucchi, Corella S., et al.
Publicado: (2012)

Interaction of Rep and DnaB on DNA
por: Atkinson, John, et al.
Publicado: (2011)

Non-coding telomeric and subtelomeric transcripts are differentially regulated by telomeric and heterochromatin assembly factors in fission yeast
por: Greenwood, Jessica, et al.
Publicado: (2012)

Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks
por: Heinz, Kathrin S, et al.
Publicado: (2018)

DNA polymerase beta participates in DNA End-joining
por: Ray, Sreerupa, et al.
Publicado: (2018)

Interaction between Escherichia coli DNA polymerase IV and single-stranded DNA-binding protein is required for DNA synthesis on SSB-coated DNA
por: Furukohri, Asako, et al.
Publicado: (2012)

Effective, homogeneous and transient interference with cytosine methylation in plant genomic DNA by zebularine
por: Baubec, Tuncay, et al.
Publicado: (2009)

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair
por: Abdou, Ismail, et al.
Publicado: (2015)

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication
por: Obi, Ikenna, et al.
Publicado: (2020)

Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing
por: He, Liu, et al.
Publicado: (2023)

Dna2 removes toxic ssDNA-RPA filaments generated from meiotic recombination-associated DNA synthesis
por: Zhai, Binyuan, et al.
Publicado: (2023)

The human HELLS chromatin remodelling protein promotes end resection to facilitate homologous recombination and contributes to DSB repair within heterochromatin
por: Kollárovič, Gabriel, et al.
Publicado: (2020)

Metal-induced DNA translocation leads to DNA polymerase conformational activation
por: Kirby, Thomas W., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_dkakp8g49d0219m474qtdcadpl