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The flip-flop configuration of the PABP-dimer leads to switching of the translation function

Poly(A)-binding protein (PABP) is a translation initiation factor that interacts with the poly(A) tail of mRNAs. PABP bound to poly(A) stimulates translation by interacting with the eukaryotic initiation factor 4G (eIF4G), which brings the 3′ end of an mRNA close to its 5′ m(7)G cap structure throug...

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Detalles Bibliográficos
Autores principales:	Gu, Sohyun, Jeon, Hyung-Min, Nam, Seung Woo, Hong, Ka Young, Rahman, Md Shafiqur, Lee, Jong-Bong, Kim, Youngjin, Jang, Sung Key
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754640/ https://www.ncbi.nlm.nih.gov/pubmed/34904669 http://dx.doi.org/10.1093/nar/gkab1205

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