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The double-stranded RNA-binding protein, Staufen1, is an IRES-transacting factor regulating HIV-1 cap-independent translation initiation

Translation initiation of the viral genomic mRNA (vRNA) of human immunodeficiency virus-type 1 (HIV-1) can be mediated by a cap- or an internal ribosome entry site (IRES)-dependent mechanism. A previous report shows that Staufen1, a cellular double-stranded (ds) RNA-binding protein (RBP), binds to t...

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Detalles Bibliográficos
Autores principales: Ramos, Hade, Monette, Anne, Niu, Meijuan, Barrera, Aldo, López-Ulloa, Brenda, Fuentes, Yazmín, Guizar, Paola, Pino, Karla, DesGroseillers, Luc, Mouland, Andrew J, López-Lastra, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754648/
https://www.ncbi.nlm.nih.gov/pubmed/34893869
http://dx.doi.org/10.1093/nar/gkab1188

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