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RNA self-splicing by engineered hairpin ribozyme variants

Small RNAs capable of self-cleavage and ligation might have been the precursors for the much more complex self-splicing group I and II introns in an early RNA world. Here, we demonstrate the activity of engineered hairpin ribozyme variants, which as self-splicing introns are removed from their paren...

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Detalles Bibliográficos
Autores principales: Hieronymus, Robert, Zhu, Jikang, Müller, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754997/
https://www.ncbi.nlm.nih.gov/pubmed/34928378
http://dx.doi.org/10.1093/nar/gkab1239