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Yearlong COVID-19 Infection Reveals Within-Host Evolution of SARS-CoV-2 in a Patient With B-Cell Depletion

B-cell–depleting therapies may lead to prolonged disease and viral shedding in individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and this viral persistence raises concern for viral evolution. We report sequencing of early and late samples from a 335-day infection...

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Detalles Bibliográficos
Autores principales: Nussenblatt, Veronique, Roder, Allison E, Das, Sanchita, de Wit, Emmie, Youn, Jung-Ho, Banakis, Stephanie, Mushegian, Alexandra, Mederos, Christopher, Wang, Wei, Chung, Matthew, Pérez-Pérez, Lizzette, Palmore, Tara, Brudno, Jennifer N, Kochenderfer, James N, Ghedin, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755281/
https://www.ncbi.nlm.nih.gov/pubmed/34940844
http://dx.doi.org/10.1093/infdis/jiab622

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