Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology

We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed among the Nordic countries of Norway, Sweden, Denmark, Finland, and Iceland. Ou...

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Autores principales: Duchene, Sebastian, Featherstone, Leo, Freiesleben de Blasio, Birgitte, Holmes, Edward C, Bohlin, Jon, Pettersson, John H O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755353/
https://www.ncbi.nlm.nih.gov/pubmed/35229003
http://dx.doi.org/10.1093/ofid/ofab665
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author Duchene, Sebastian
Featherstone, Leo
Freiesleben de Blasio, Birgitte
Holmes, Edward C
Bohlin, Jon
Pettersson, John H O
author_facet Duchene, Sebastian
Featherstone, Leo
Freiesleben de Blasio, Birgitte
Holmes, Edward C
Bohlin, Jon
Pettersson, John H O
author_sort Duchene, Sebastian
collection PubMed
description We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed among the Nordic countries of Norway, Sweden, Denmark, Finland, and Iceland. Our results suggest that although geographical connectivity, population density, and openness influence the spread and the size of SARS-CoV-2 transmission clusters, the different country-specific intervention strategies had the largest impact. We also found a significant positive association between the size and duration of transmission clusters in the Nordic countries, suggesting that the rapid deployment of contact tracing is a key response measure in reducing virus transmission.
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spelling pubmed-87553532022-01-13 Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology Duchene, Sebastian Featherstone, Leo Freiesleben de Blasio, Birgitte Holmes, Edward C Bohlin, Jon Pettersson, John H O Open Forum Infect Dis Brief Report We explored how the duration, size, and number of virus transmission clusters, defined as country-specific monophyletic groups in a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) phylogenetic tree, differed among the Nordic countries of Norway, Sweden, Denmark, Finland, and Iceland. Our results suggest that although geographical connectivity, population density, and openness influence the spread and the size of SARS-CoV-2 transmission clusters, the different country-specific intervention strategies had the largest impact. We also found a significant positive association between the size and duration of transmission clusters in the Nordic countries, suggesting that the rapid deployment of contact tracing is a key response measure in reducing virus transmission. Oxford University Press 2022-01-03 /pmc/articles/PMC8755353/ /pubmed/35229003 http://dx.doi.org/10.1093/ofid/ofab665 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Duchene, Sebastian
Featherstone, Leo
Freiesleben de Blasio, Birgitte
Holmes, Edward C
Bohlin, Jon
Pettersson, John H O
Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title_full Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title_fullStr Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title_full_unstemmed Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title_short Assessment of Coronavirus Disease 2019 Intervention Strategies in the Nordic Countries Using Genomic Epidemiology
title_sort assessment of coronavirus disease 2019 intervention strategies in the nordic countries using genomic epidemiology
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755353/
https://www.ncbi.nlm.nih.gov/pubmed/35229003
http://dx.doi.org/10.1093/ofid/ofab665
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