Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity

We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean tite...

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Detalles Bibliográficos
Autores principales: Shah, Melisa M, Rasheed, Mohammad Ata Ur, Harcourt, Jennifer L, Abedi, Glen R, Stumpf, Megan M, Kirking, Hannah L, Tamin, Azaibi, Mills, Lisa, Armstrong, Madeleine, Salvatore, Phillip P, Surasi, Krishna, Scott, Sarah E, Killerby, Marie E, Briggs-Hagen, Melissa, Saydah, Sharon, Tate, Jacqueline E, Fry, Alicia M, Hall, Aron J, Thornburg, Natalie J, Midgley, Claire M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755399/
https://www.ncbi.nlm.nih.gov/pubmed/35141347
http://dx.doi.org/10.1093/ofid/ofab664
Descripción
Sumario:We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean titers of 117.2 BAU/mL and 84.0 BAU/mL at 6 and 12 months, respectively.

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