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Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity

We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean tite...

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Autores principales: Shah, Melisa M, Rasheed, Mohammad Ata Ur, Harcourt, Jennifer L, Abedi, Glen R, Stumpf, Megan M, Kirking, Hannah L, Tamin, Azaibi, Mills, Lisa, Armstrong, Madeleine, Salvatore, Phillip P, Surasi, Krishna, Scott, Sarah E, Killerby, Marie E, Briggs-Hagen, Melissa, Saydah, Sharon, Tate, Jacqueline E, Fry, Alicia M, Hall, Aron J, Thornburg, Natalie J, Midgley, Claire M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755399/
https://www.ncbi.nlm.nih.gov/pubmed/35141347
http://dx.doi.org/10.1093/ofid/ofab664
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author Shah, Melisa M
Rasheed, Mohammad Ata Ur
Harcourt, Jennifer L
Abedi, Glen R
Stumpf, Megan M
Kirking, Hannah L
Tamin, Azaibi
Mills, Lisa
Armstrong, Madeleine
Salvatore, Phillip P
Surasi, Krishna
Scott, Sarah E
Killerby, Marie E
Briggs-Hagen, Melissa
Saydah, Sharon
Tate, Jacqueline E
Fry, Alicia M
Hall, Aron J
Thornburg, Natalie J
Midgley, Claire M
author_facet Shah, Melisa M
Rasheed, Mohammad Ata Ur
Harcourt, Jennifer L
Abedi, Glen R
Stumpf, Megan M
Kirking, Hannah L
Tamin, Azaibi
Mills, Lisa
Armstrong, Madeleine
Salvatore, Phillip P
Surasi, Krishna
Scott, Sarah E
Killerby, Marie E
Briggs-Hagen, Melissa
Saydah, Sharon
Tate, Jacqueline E
Fry, Alicia M
Hall, Aron J
Thornburg, Natalie J
Midgley, Claire M
author_sort Shah, Melisa M
collection PubMed
description We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean titers of 117.2 BAU/mL and 84.0 BAU/mL at 6 and 12 months, respectively.
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spelling pubmed-87553992022-01-13 Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity Shah, Melisa M Rasheed, Mohammad Ata Ur Harcourt, Jennifer L Abedi, Glen R Stumpf, Megan M Kirking, Hannah L Tamin, Azaibi Mills, Lisa Armstrong, Madeleine Salvatore, Phillip P Surasi, Krishna Scott, Sarah E Killerby, Marie E Briggs-Hagen, Melissa Saydah, Sharon Tate, Jacqueline E Fry, Alicia M Hall, Aron J Thornburg, Natalie J Midgley, Claire M Open Forum Infect Dis Brief Report We quantify antibody and memory B-cell responses to severe acute respiratory syndrome coronavirus 2 at 6 and 12 months postinfection among 7 unvaccinated US coronavirus disease 2019 cases. All had detectable S-specific memory B cells and immunoglobulin G at both time points, with geometric mean titers of 117.2 BAU/mL and 84.0 BAU/mL at 6 and 12 months, respectively. Oxford University Press 2022-01-05 /pmc/articles/PMC8755399/ /pubmed/35141347 http://dx.doi.org/10.1093/ofid/ofab664 Text en Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022. This work is written by (a) US Government employee(s) and is in the public domain in the US.
spellingShingle Brief Report
Shah, Melisa M
Rasheed, Mohammad Ata Ur
Harcourt, Jennifer L
Abedi, Glen R
Stumpf, Megan M
Kirking, Hannah L
Tamin, Azaibi
Mills, Lisa
Armstrong, Madeleine
Salvatore, Phillip P
Surasi, Krishna
Scott, Sarah E
Killerby, Marie E
Briggs-Hagen, Melissa
Saydah, Sharon
Tate, Jacqueline E
Fry, Alicia M
Hall, Aron J
Thornburg, Natalie J
Midgley, Claire M
Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title_full Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title_fullStr Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title_full_unstemmed Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title_short Twelve-Month Follow-up of Early COVID-19 Cases in the United States: Cellular and Humoral Immune Longevity
title_sort twelve-month follow-up of early covid-19 cases in the united states: cellular and humoral immune longevity
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755399/
https://www.ncbi.nlm.nih.gov/pubmed/35141347
http://dx.doi.org/10.1093/ofid/ofab664
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