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Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

With the outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), coronaviruses have begun to attract great attention across the world. Of the known human coronaviruses, however, Middle East respiratory syndrome coronavirus (MERS-CoV) is the most lethal. Coronavirus proteins can be...

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Detalles Bibliográficos
Autores principales: Zhou, Yuzheng, Zheng, Rong, Liu, Sixu, Disoma, Cyrollah, Du, Ashuai, Li, Shiqin, Chen, Zongpeng, Dong, Zijun, Zhang, Yongxing, Li, Sijia, Liu, Pinjia, Razzaq, Aroona, Chen, Xuan, Liao, Yujie, Tao, Siyi, Liu, Yuxin, Xu, Lunan, Zhang, Qianjun, Peng, Jian, Deng, Xu, Li, Shanni, Jiang, Taijiao, Xia, Zanxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755419/
https://www.ncbi.nlm.nih.gov/pubmed/35032548
http://dx.doi.org/10.1016/j.jbc.2022.101584