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Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing

BACKGROUND AND OBJECTIVES: To examine the maturational status of the auditory cortex in adults with cochlear implants (CIs) using the latencies of the P1, N1, and P2 components of cortical auditory-evoked potentials (CAEPs). SUBJECTS AND METHODS: A total of 25 adults with CIs and 25 age-matched, nor...

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Autores principales: Boo, Seong-Hyun, Jeong, Sung Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Audiological Society and Korean Otological Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755439/
https://www.ncbi.nlm.nih.gov/pubmed/34719150
http://dx.doi.org/10.7874/jao.2021.00339
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author Boo, Seong-Hyun
Jeong, Sung Wook
author_facet Boo, Seong-Hyun
Jeong, Sung Wook
author_sort Boo, Seong-Hyun
collection PubMed
description BACKGROUND AND OBJECTIVES: To examine the maturational status of the auditory cortex in adults with cochlear implants (CIs) using the latencies of the P1, N1, and P2 components of cortical auditory-evoked potentials (CAEPs). SUBJECTS AND METHODS: A total of 25 adults with CIs and 25 age-matched, normal-hearing control subjects participated in this study. Specifically, patients with CIs were divided into three groups depending on their age of deafness onset: Group A comprised patients with prelingual deafness who had received CI during early childhood (n=7), Group B comprised patients with early childhood-onset, progressive deafness who had received CI during childhood (n=6), and Group C comprised patients with adult-onset deafness (n=12). The P1, N1, and P2 latencies of their CAEPs were then compared between CI patients and normal-hearing subjects. RESULTS: All participants showed clear CAEP responses. P1 and N1 latencies in Group A and Group C patients were significantly longer than those in the control group. Meanwhile, Group B patients had significantly longer N1 and P2 latencies, as compared with those in the control group. CONCLUSIONS: Patients with prelingual deafness and those with early-childhood onset, progressive deafness who received CI developed primary and higher-order auditory areas postoperatively when they became adults. However, their auditory cortex maturational statuses seemed to be worse than that of normal-hearing individuals. Furthermore, adult patients with late-onset deafness might experience degenerative auditory cortex changes during the auditory deprivation period between deafness onset and cochlear implantation.
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spelling pubmed-87554392022-01-20 Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing Boo, Seong-Hyun Jeong, Sung Wook J Audiol Otol Original Article BACKGROUND AND OBJECTIVES: To examine the maturational status of the auditory cortex in adults with cochlear implants (CIs) using the latencies of the P1, N1, and P2 components of cortical auditory-evoked potentials (CAEPs). SUBJECTS AND METHODS: A total of 25 adults with CIs and 25 age-matched, normal-hearing control subjects participated in this study. Specifically, patients with CIs were divided into three groups depending on their age of deafness onset: Group A comprised patients with prelingual deafness who had received CI during early childhood (n=7), Group B comprised patients with early childhood-onset, progressive deafness who had received CI during childhood (n=6), and Group C comprised patients with adult-onset deafness (n=12). The P1, N1, and P2 latencies of their CAEPs were then compared between CI patients and normal-hearing subjects. RESULTS: All participants showed clear CAEP responses. P1 and N1 latencies in Group A and Group C patients were significantly longer than those in the control group. Meanwhile, Group B patients had significantly longer N1 and P2 latencies, as compared with those in the control group. CONCLUSIONS: Patients with prelingual deafness and those with early-childhood onset, progressive deafness who received CI developed primary and higher-order auditory areas postoperatively when they became adults. However, their auditory cortex maturational statuses seemed to be worse than that of normal-hearing individuals. Furthermore, adult patients with late-onset deafness might experience degenerative auditory cortex changes during the auditory deprivation period between deafness onset and cochlear implantation. The Korean Audiological Society and Korean Otological Society 2022-01 2021-11-01 /pmc/articles/PMC8755439/ /pubmed/34719150 http://dx.doi.org/10.7874/jao.2021.00339 Text en Copyright © 2022 The Korean Audiological Society and Korean Otological Society https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Boo, Seong-Hyun
Jeong, Sung Wook
Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title_full Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title_fullStr Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title_full_unstemmed Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title_short Cortical Auditory Evoked Potential in Adults With Cochlear Implants: A Comparison With Adults With Normal Hearing
title_sort cortical auditory evoked potential in adults with cochlear implants: a comparison with adults with normal hearing
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755439/
https://www.ncbi.nlm.nih.gov/pubmed/34719150
http://dx.doi.org/10.7874/jao.2021.00339
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