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Trained immunity induction by the inactivated mucosal vaccine MV130 protects against experimental viral respiratory infections

MV130 is an inactivated polybacterial mucosal vaccine that confers protection to patients against recurrent respiratory infections, including those of viral etiology. However, its mechanism of action remains poorly understood. Here, we find that intranasal prophylaxis with MV130 modulates the lung i...

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Detalles Bibliográficos
Autores principales: Brandi, Paola, Conejero, Laura, Cueto, Francisco J., Martínez-Cano, Sarai, Dunphy, Gillian, Gómez, Manuel J., Relaño, Carlos, Saz-Leal, Paula, Enamorado, Michel, Quintas, Ana, Dopazo, Ana, Amores-Iniesta, Joaquín, del Fresno, Carlos, Nistal-Villán, Estanislao, Ardavín, Carlos, Nieto, Antonio, Casanovas, Miguel, Subiza, José Luis, Sancho, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755442/
https://www.ncbi.nlm.nih.gov/pubmed/34986349
http://dx.doi.org/10.1016/j.celrep.2021.110184

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