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TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growth

The embryonic transcription factors TWIST1/2 are frequently overexpressed in cancer, acting as multifunctional oncogenes. Here we investigate their role in neuroblastoma (NB), a heterogeneous childhood malignancy ranging from spontaneous regression to dismal outcomes despite multimodal therapy. We f...

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Detalles Bibliográficos
Autores principales: Sepporta, Maria-Vittoria, Praz, Viviane, Balmas Bourloud, Katia, Joseph, Jean-Marc, Jauquier, Nicolas, Riggi, Nicolò, Nardou-Auderset, Katya, Petit, Audrey, Scoazec, Jean-Yves, Sartelet, Hervé, Renella, Raffaele, Mühlethaler-Mottet, Annick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755726/
https://www.ncbi.nlm.nih.gov/pubmed/35022561
http://dx.doi.org/10.1038/s42003-021-02958-6