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TWIST1 expression is associated with high-risk neuroblastoma and promotes primary and metastatic tumor growth
The embryonic transcription factors TWIST1/2 are frequently overexpressed in cancer, acting as multifunctional oncogenes. Here we investigate their role in neuroblastoma (NB), a heterogeneous childhood malignancy ranging from spontaneous regression to dismal outcomes despite multimodal therapy. We f...
Autores principales: | Sepporta, Maria-Vittoria, Praz, Viviane, Balmas Bourloud, Katia, Joseph, Jean-Marc, Jauquier, Nicolas, Riggi, Nicolò, Nardou-Auderset, Katya, Petit, Audrey, Scoazec, Jean-Yves, Sartelet, Hervé, Renella, Raffaele, Mühlethaler-Mottet, Annick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755726/ https://www.ncbi.nlm.nih.gov/pubmed/35022561 http://dx.doi.org/10.1038/s42003-021-02958-6 |
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