Postmortem high-dimensional immune profiling of severe COVID-19 patients reveals distinct patterns of immunosuppression and immunoactivation

A complete diagnostic autopsy is the gold-standard to gain insight into Coronavirus disease 2019 (COVID-19) pathogenesis. To delineate the in situ immune responses to SARS-CoV-2 viral infection, here we perform comprehensive high-dimensional transcriptional and spatial immune profiling in 22 COVID-1...

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Detalles Bibliográficos
Autores principales: Wu, Haibo, He, Peiqi, Ren, Yong, Xiao, Shiqi, Wang, Wei, Liu, Zhenbang, Li, Heng, Wang, Zhe, Zhang, Dingyu, Cai, Jun, Zhou, Xiangdong, Jiang, Dongpo, Fei, Xiaochun, Zhao, Lei, Zhang, Heng, Liu, Zhenhua, Chen, Rong, Li, Weiqing, Wang, Chaofu, Zhang, Shuyang, Qin, Jiwei, Nashan, Björn, Sun, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755743/
https://www.ncbi.nlm.nih.gov/pubmed/35022412
http://dx.doi.org/10.1038/s41467-021-27723-5

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