Enteric α-synuclein impairs intestinal epithelial barrier through caspase-1-inflammasome signaling in Parkinson’s disease before brain pathology

Bowel inflammation, impaired intestinal epithelial barrier (IEB), and gut dysbiosis could represent early events in Parkinson’s disease (PD). This study examined, in a descriptive manner, the correlation among enteric α-synuclein, bowel inflammation, impairments of IEB and alterations of enteric bac...

Descripción completa

Detalles Bibliográficos
Autores principales: Pellegrini, C., D’Antongiovanni, V., Miraglia, F., Rota, L., Benvenuti, L., Di Salvo, C., Testa, G., Capsoni, S., Carta, G., Antonioli, L., Cattaneo, A., Blandizzi, C., Colla, E., Fornai, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755783/
https://www.ncbi.nlm.nih.gov/pubmed/35022395
http://dx.doi.org/10.1038/s41531-021-00263-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755783/
https://www.ncbi.nlm.nih.gov/pubmed/35022395
http://dx.doi.org/10.1038/s41531-021-00263-x

Ejemplares similares