Connexin 43 confers chemoresistance through activating PI3K

Circumventing chemoresistance is crucial for effectively treating cancer including glioblastoma, a lethal brain cancer. The gap junction protein connexin 43 (Cx43) renders glioblastoma resistant to chemotherapy; however, targeting Cx43 is difficult because mechanisms underlying Cx43-mediated chemore...

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Detalles Bibliográficos
Autores principales: Pridham, Kevin J., Shah, Farah, Hutchings, Kasen R., Sheng, Kevin L., Guo, Sujuan, Liu, Min, Kanabur, Pratik, Lamouille, Samy, Lewis, Gabrielle, Morales, Marc, Jourdan, Jane, Grek, Christina L., Ghatnekar, Gautam G., Varghese, Robin, Kelly, Deborah F., Gourdie, Robert G., Sheng, Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755794/
https://www.ncbi.nlm.nih.gov/pubmed/35022385
http://dx.doi.org/10.1038/s41389-022-00378-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755794/
https://www.ncbi.nlm.nih.gov/pubmed/35022385
http://dx.doi.org/10.1038/s41389-022-00378-7

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