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Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma
Despite remarkable advances in therapeutic interventions, malignant melanoma (MM) remains a life-threating disease. Following high initial response rates to targeted kinase-inhibition metastases quickly acquire resistance and present with enhanced tumor progression and invasion, demanding alternativ...
Autores principales: | Del Mistro, Greta, Riemann, Shamala, Schindler, Sebastian, Beissert, Stefan, Kontermann, Roland E., Ginolhac, Aurelien, Halder, Rashi, Presta, Luana, Sinkkonen, Lasse, Sauter, Thomas, Kulms, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755828/ https://www.ncbi.nlm.nih.gov/pubmed/35022419 http://dx.doi.org/10.1038/s41419-022-04502-8 |
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